Yang Y, Wang TY, Li Q, Lu J, Ren Y, Weiner AB, Fry J, Liu Q, Yum C, Wang R, Guo Q, Wan Y, Ji Z, Dong X, Lotan TL, Schaeffer EM, Yang R, Cao Q. Androgen receptor-regulated lncRNA PRCAT71 promotes AR signaling through the interaction with KHSRP in prostate cancer. Sci Adv. 2025 Apr 11;11(15):eadk6989. doi: 10.1126/sciadv.adk6989. PMID: 40203114
Matias-Barrios VM, Radaeva M, Rosellinny G, Jia Q, Xie N, Villanueva M, Ibrahim H, Smith J, Gleave M, Lallous N, Straus SK, Cherkasov A, Dong X. Developing novel Lin28 inhibitors by computer aided drug design. Cell Death Discov. 2025 Jan 12;11(1):5. doi: 10.1038/s41420-024-02281-z. PMID: 39800739
Wang Y, Scurll J, Rascón IA, Cui C, Ni Y, Shi AM, Gangadharannambiar P, Wang Y, Akamatsu S, Beltran H, Cox M, Crea F, Daugaard M, Dong X, Haffner M, He H, Jachetti E, Kyprianou N, Li B, Ong CE, Rickman DS, Sen T, Zhu HH, Zoubeidi A, Gleave ME. The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions. Epigenomics. 2024;16(17):1129-1132. doi: 10.1080/17501911.2024.2391729. PMID: 39225130
Pornour M, Jeon HY, Ryu H, Khadka S, Xu R, Chen H, Hussain A, Lam HM, Zhuang Z, Oo HZ, Gleave M, Dong X, Wang Q, Barbieri C, Qi J. USP11 promotes prostate cancer progression by up-regulating AR and c-Myc activity. Proc Natl Acad Sci USA. 2024 Jul 30;121(31):e2403331121. doi: 10.1073/pnas.2403331121. PMID: 39052835
Li Y, Lv L, Ye M, Xie N, Fazli L, Wang Y, Wang W, Yang S, Ni Q, Chen J, Guo X, Zhao Y, Xue G, Sha J, Dong X, Zhang L. PDIA2 has a dual function in promoting androgen deprivation therapy induced venous thrombosis events and castrate resistant prostate cancer progression. Oncogene. 2024 May;43(21):1631-1643. doi: 10.1038/s41388-024-03024-1. PMID: 38589675.
Jeon, Hee-Young; Pornour, Majid ; Ryu, Hyunju ; Khadka, Sudeep ; Xu, Rui; Jang, Jihyun ; Li, Deqiang ; Chen, Hegang ; Hussain, Arif; Fazli, Ladan ; Gleave, Martin; Dong, Xuesen; Huang, Furong; Wang, Qianben; Barbieri, Christopher ; Qi, Jianfei SMAD3 promotes expression and activity of the androgen receptor in prostate cancer. Nucleic Acids Research 2023 Feb 2;gkad043. PMID: 36727462
Liancheng Fan, Yiming Gong, Yuman He, Wei-Qiang Gao, Xuesen Dong, Baijun Dong, Helen He Zhu, Wei Xue. TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment-induced neuroendocrine differentiation in prostate cancer. Oncogene. 2023 Feb;42(8):559-571. PMID: 36544044
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish Choudhury, Kent Mouw, Zoltan Szallasi, Lee Zou, Adam Kibel, and Li Jia CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer Nature Communications 2023 Jan 17;14(1):252. PMID: 36650183
Baraa Orabi, Ning Xie, Brian McConeghy, Xuesen Dong, Cedric Chauve, Faraz Hach. Freddie: annotation-independent detection and discovery of transcriptomic alternative splicing isoforms using long-read sequencing. Nucleic Acids Res. 2023 Jan 25;51(2):e11. doi: 10.1093/nar/gkac1112. PMID: 36478271
Matias-Barrios VM. Xuesen Dong The Implication of Topoisomerase II Inhibitors in Synthetic Lethality for Cancer Therapy. Pharmaceuticals. 2023 January; 16(1):94.
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Radaeva M, Ho C, Xie N, Zhang S, Lee J, Liu L, Lallous N, Cherkasov A, Dong X. Discovery of Novel Lin28 Inhibitors to Suppress Cancer Cell Stemness. Cancers (Basel). 2022 November; 14(22):5687.
Yi Y, Li Y, Meng Q, Li Q, Li F, Lu B, Fazli L, Zhao D, Li C, Jiang W, Wang R, Liu Q, Szczepanski A, Li Q, Ji Z, Kalantry S, Wang L, Dong X, Chen K, Zhao W, Cao Q Nature Cell Biology. 2021 Apr;23(4):341-354. PMID: 33795875
Gao L, Zhang W, Zhang J, Liu J, Sun F, Liu H, Hu J, Wang X, Wang X, Su P, Chen S, Qu S, Shi B, Xiong X, Chen W, Dong X*, Han B*. KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer. Cancer Res. 2021 Feb 15;81(4):1026-1039.
Lovnicki J, Gan Y, Feng T, Li Y, Xie N, Ho CH, Lee AR, Chen X, Nappi L, Han B, Fazli L, Huang J, Gleave ME, Dong X. LIN28B promotes the development of neuroendocrine prostate cancer. J Clin Invest. 2020 Aug 31;135373.
Dong X, Chen R. Understanding aberrant RNA splicing to facilitate cancer diagnosis and therapy Oncogene. 2020 Mar;39(11):2231-2242. doi: 10.1038/s41388-019-1138-2.
Li Y, Xie N, Chen R, Lee AR, Lovnicki J, Morrison EA, Fazli L, Zhang Q, Musselman CA, Wang Y, Huang J, Gleave ME, Collins C, Dong X. RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression. European Urology. 2019 Aug; 76(2):157-166
Luo J, Li Y, Zheng W, Xie N, Shi Y, Long Z, Xie L, Fazli L, Zhang D, Gleave M, Dong X. Characterization of a Prostate- and Prostate Cancer-Specific Circular RNA Encoded by the Androgen Receptor Gene. Mol Ther Nucleic Acids. 2019 Dec 6;18:916-926.
Fan L, Zhang F, Xu S, Cui X, Hussain A, Fazli L, Gleave M, Dong X, Qi J. Histone demethylase JMJD1A promotes alternative splicing of AR variant 7 (AR-V7) in prostate cancer cells. Proc Natl Acad Sci USA. 2018 May 15;115(20):E4584-E4593.
Lee AR, Gan Y, Tang Y, Dong X. A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network. EBioMedicine. 2018 Sep;35:167-177.
Zhu S, Zhao D, Yan L, Jiang W, Kim JS, Gu B, Liu Q, Wang R, Xia B, Zhao JC, Song G, Mi W, Wang RF, Shi X, Lam HM, Dong X, Yu J, Chen K, Cao Q. BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1. Nat Commun. 2018 Feb 5;9(1):500.
Li Y, Donmez N, Sahinalp C, Xie N, Wang Y, Xue H, Beltran H, Gleave ME, Wang Y, Collins C, Dong X. SRRM4 Drives Neuroendocrine Transdifferentiation of Prostate Adenocarcinoma under AR Pathway Inhibition. European Urology 2017 Jan;71(1):68-78.
Nadeem L, Shynlova O, Matysiak-Zablocki E, Mesiano S, Dong X*, Lye S*. Molecular Evidence of Functional Progesterone Withdrawal in Human Myometrium. Nature Communications 2016 May 25;7:11565.
Liu LL, Xie N, Sun S, Plymate S, Mostaghel E, Dong X. Mechanisms of the androgen receptor splicing in prostate cancer cells. Oncogene. 2014 Jun 12;33(24):3140-50.
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